https://www.ceesdekker.net - An Overview
https://www.ceesdekker.net - An Overview
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Halfway by way of his career, Cees Dekker reinvented himself. Immediately after many years of hardcore physics, he shifted his concentration to ‘nanobiology’ in the transform from the millennium. A expression he coined himself, like a make any difference of truth.
Our group experiments bacterial mobile division and is also aiming to constitute a ‘base up biology’ in artificial cells that will autonomously divide. Our primary desire lies in mobile division, chromatin construction, and spatial control.
Across the same time, the team of Paul McEuen, who was then primarily based within the University of California, Berkeley, confirmed very similar final results on ropes of bundled nanotubes. Based on the wrapping angle, nanotubes can are available metallic or semiconducting variants, a prediction that we and Charles Lieber’s group at Harvard College independently confirmed applying scanning tunnelling spectroscopy experiments.
Sadly, For several years following Iijima’s report, the creation of thoroughly clean nanotubes was cumbersome. In 1996, on the other hand, the group of Richard Smalley at Rice University managed to generate single-walled carbon nanotubes at significant yield. Soon immediately after, I contacted Smalley, and we made a decision to join forces to evaluate the transportation via a one carbon nanotube.
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Immediate immobilization of native yeast iso-1 cytochrome c on bare gold: fast electron relay to redox enzymes and zeptomole protein-movie voltammetry
All parameters had been the identical for every panel ceesdekker.net With this online video, aside from the initial placement from the 6hb rod (proven in blue) within the nanopore. Simulations that terminated early resulting from translocation of your rod in the pore are marked by a gray history.
Learning DNA loop extrusion by SMC proteins for chromosome architecture with one-molecule assays.
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It absolutely was during this period that Dekker carried out analysis on magnetic spin programs and on sounds in superconductors and semiconductors.
In 1993 he was appointed as Affiliate Professor at Delft University of Technological innovation. From the mid-1990s Dekker and his crew accomplished achievements with the discovery on the Digital properties of carbon nanotubes, the 1st one-molecule transistor along with other nanoscience.
Many new phenomena ended up uncovered, and he and his study group recognized a number one placement Within this industry of analysis. Dekker and his research team discovered new physics of nanotubes together with explored the feasibility of molecular electronics. In 1998, they have been the first to develop a transistor according to one nanotube molecule.
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Sound-condition nanopores have confirmed for being a astonishingly adaptable probe for solitary-molecule Examination of DNA. I will describe a few of our latest findings – especially DNA knots – along with our attempts to broaden the capabilities of solid-state nanopores even further more, during the way of one-protein detection, graphene nanopores, plasmonic nanopores, and DNA origami nanopores.